Plantar pressure distribution is closely related to human health, and abnormal changes in plantar pressure distribution are early symptoms of some foot diseases. To help patients prevent foot diseases and monitor the distribution of plantar pressure in real-time, a dynamic plantar pressure distribution measurement system based on a tactile sensing array is developed. The system has a total of 48 sensing units, and the measurement error is less than 2. 4% , which can accurately collect the pressure of each area of the sole of the foot. The system adopts a wearable design, the data acquisition system is fixed on the ankle, then connected to the host computer through Bluetooth. In addition, the traditional pressure analysis method cannot analyze the pressure distribution change during exercise. To address this issue, a dynamic plantar pressure distribution analysis method is proposed. The plantar pressure data of the human body are classified by the support vector machine, and the classification accuracy rate is 98. 6% . On this basis, the typical pressure distribution index of the gait phase is introduced, which is combined with the traditional analysis index to realize the analysis of human health status and evaluation. Experiments have shown that the system can accurately measure the plantar pressure distribution under exercise conditions, analyze pressure distribution changes under abnormal conditions, and give early warning to abnormal areas.